Scientist, Molecular Discovery

The Merck Exploratory Science Center in Cambridge provides a unique experience to contribute to Merck’s drug discovery efforts at one of the earliest stages of the process. To this end, we strive to create a fast-paced, nimble and flexible environment of mutual respect, creativity, invention and teamwork. The incumbent will be part of a highly collaborative and innovative scientific culture with the ultimate goal of learning new biology, chemistry, and developing technology that drives therapeutic development. 

 

Therefore, we are seeking an innovative chemical biologist to work with a diverse group of scientists leading research on novel targets discovery from the bench. This is an exciting opportunity for a B.S. or M.S. level individual with chemistry, chemical biology, biochemistry, or a related field. 

·   The successful candidate will be able to design cell-based experiments to validate novel targets, target molecules, and new chemical biology assays

·  Design, synthesize, purify and characterize drug candidates and/or chemical probes (small molecule and peptide) to solve various chemical biology problems

·    Selection and application of appropriate purification techniques including flash chromatography, high performance liquid chromatography (HPLC)

·     Acquisition and interpretation of analytical data such as NMR and LC/MS

·    Become part of a creative and flexible team; collaborate and work closely with other scientists.

·  Contribute to experimental design, analysis, and interpretation of experiments

·    Collaborate with variety of teams to execute on chemical biology-based platform builds

·    Function and communicate effectively in a highly productive multi-disciplinary environment

·    Act as a leader in the laboratory, executing on program and chemistry strategy