CRISPR Research Associate/Senior Research Associate Synthetic Biology
We are seeking a Research Associate to improve laboratory processes and support metabolic engineering and characterization of LanzaTech’s proprietary gas fermenting microbes. The Research Associate will be joining LanzaTech’s Synthetic Biology team, working in the lab and interacting with other teams across the company. This role will support Senior Scientists on project-based work as well as a variety of lab management tasks. The Research Associate will work towards both specific goals and towards improving workflows to benefit all Synthetic Biology team members. Types of activities include plasmid construction, bacterial transformation and culturing, confirmation of clones, product screening, genetic parts characterization, curating strain and plasmid repositories, preparing buffer and media, stocking consumables, authoring training and protocol documents, etc.
Duties & Responsibilities:
- Design, cloning and assembly of multi-fragment DNA constructs for heterologous pathway expression
- Genetic modification and selection of LanzaTech proprietary microbes
- High-throughput cultivation and screening of LanzaTech proprietary microbes
- Analysis of data and interpretation of results against model predictions
- Use of computational tools and databases
- Learn established workflows and implement improvements
- Support organization of training, protocol, and other document development
- Assist in general lab chores such as solution prep, cleaning, organization, etc.
- Maintain a laboratory notebook, track and QC data in LIMS system as required
- Attend seminars and participate in group and project meetings and lab activities
Requirements:
- M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field with preferable 1-2 years of relevant experience in a laboratory setting
- Hands-on experience in cloning and assembly of DNA and growth of microbes
- Use of DNA design software, word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data
- Strong organizational, time management, record keeping, and prioritization skills
- Independent, hard-working, and highly self-motivated
- Excellent communication and interpersonal relationship skills
- Ability to maintain a positive attitude when faced with challenges
- Desire to work in a team and assist other team members
- Awareness of safety issues in the work environment
Highly preferred:
- Experience in biotech industry
- Experience with metabolic engineering
- Experience different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination
- Experience working with genetic and metabolic pathway databases and DNA design software
- Experience with gas fermentation
- Experience working with anaerobic microbes
- Strong computer literacy, including Office, SharePoint; Experience in scripting and working with large datasets is preferred
- Ability to conduct research independently and manage multiple tasks in parallel
Location
- LanzaTech Headquarters
- Skokie, IL USA
https://lanzatech.applytojob.com/apply/R1aZVpu0fc/Synthetic-Biology-Research-Associate?referrer=20211114025052ZHQAUES5DJ9OQVAJ