Scientist - Antibody Engineer
Position Summary
We are seeking a Scientist to join our Antibody Research team which drives development of CST’s antibody technologies of the future. This individual will work in a highly collaborative environment applying antibody and protein engineering, mammalian construct design, and state-of-the-art molecular biology techniques to our extensive catalog of recombinant antibodies. S/he will focus on innovating and developing new engineered antibody product opportunities, as well as enhancing our current products.
Responsibilities
- Design and construct novel antibody variants to be used in a variety of different assay platforms
- Design and construct antibody-based scaffolds and fusion proteins
- Express and characterize these molecules in vitro using biochemical and cell-based assays
- Actively drive exploratory activities from the bench
- Share and contribute scientific expertise with team members
- Continuously identify and help to drive technological advancements that lead to more efficient and scalable means of antibody development
Qualifications
- Ph.D. in biomedical sciences, structural biology, or engineering or related degree plus 2 years postgraduate
Preferred Skills/Experience
- Experience with molecule design including Fc engineering, multi-specific antibodies, fusion proteins, and optimization of antibody-based scaffolds
- Expertise in molecular biology tasks such as PCR-based cloning, construct design, site-directed mutagenesis, and vector engineering
- Experience with protein binding assays (Octet, Biacore, ELISA etc.)
- Knowledge of antibody optimization techniques such as affinity maturation a plus
- Experience independently designing, executing, and interpreting scientific experiments
- Previous work experience in biotechnology and/or pharmaceutical drug development is desirable
- Passion for science, innovation and creative mind
- Experience writing, contributing to and publishing scientific papers
- Proven experience working in a collaborative team environment
- Demonstrated ability to meet deadlines for multiple projects and priorities simultaneously in a fast-paced environment
- Self-motivated and comfortable working independently or in cross- functional teams
- Excellent oral and written communication skills are required